Trimethoprim/sulfamethoxazole resistance in Burkholderia pseudomallei
نویسندگان
چکیده
منابع مشابه
Antimicrobial resistance in Burkholderia pseudomallei.
Four strains of Burkholderia pseudomallei were used to determine the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and time-kill curves with 13 single antimicrobial agents: ceftazidime, piperacillin, imipenem, amoxicillin/clavulanic acid, doxycycline, cotrimoxazole, kanamycin, rifampicin, ciprofloxacin, trovafloxacin, clarithromycin, azithromycin and meropenem...
متن کاملAminoglycoside and macrolide resistance in Burkholderia pseudomallei.
We were very interested in the recent paper by Moore et al. (3) in which the authors used transposon mutants to demonstrate efflux-mediated resistance to aminoglycosides and macrolides in Burkholderia (formerly Pseudomonas) pseudomallei. Melioidosis is very difficult to treat because of intrinsic resistance to many antimicrobial agents, particularly the aminoglycosides. Aminoglycoside–b-lactam ...
متن کاملTrimethoprim/sulfamethoxazole resistance in Burkholderia pseudomallei
Schetz M. Drug dosing in continuous renal replacement therapy: general rules. Curr Opin Crit Care 2007;13:645–51. Pea F, Viale P, Pavan F, Furlanut M. Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy. Clin Pharmacokinet 2007;46:997–1038. Vandecasteele SJ, De Vriese AS. Recent changes in vancomycin use in renal failure. Kidney Int 2010;77:7...
متن کاملEfflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.
Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a wide range of antimicrobial agents including beta-lactams, aminoglycosides, macrolides, and polymyxins. We used Tn5-OT182 to mutagenize B. pseudomallei to identify the genes involved in aminoglycoside resistance. We report here on the identification of AmrAB-OprA, a multidrug efflux system in B. pseud...
متن کاملPorin Involvement in Cephalosporin and Carbapenem Resistance of Burkholderia pseudomallei
BACKGROUND Burkholderia pseudomallei (Bps) is a Gram-negative bacterium that causes frequently lethal melioidosis, with a particularly high prevalence in the north and northeast of Thailand. Bps is highly resistant to many antimicrobial agents and this resistance may result from the low drug permeability of outer membrane proteins, known as porins. PRINCIPAL FINDINGS Microbiological assays sh...
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ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2014
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2014.06.003